WINPAIN Capsule

Moderate to severe pain.

Dosage & Administration

The dosage should be adjusted to the intensity of pain and the individuals response to the analgesic action of Winpain.

Adults and children over the age of 14 years:

Moderate pain: Initial dose of 50mg, followed by 50mg or 100mg 4-6 hourly.

Moderately severe pain: Initial dose of 50mg or 100mg followed by 50mg or 100mg 4-6 hourly. A total oral daily dose of 400mg must not be exceeded.

Elderly:

The usual dosages may be used except in patients 75 years of age and over, a downward adjustment of the dose and/or prolongation of the interval between doses are recommended.

Tramadol Hydrochloride is contraindicated in known hypersensitivity to Tramadol Hydrochloride or opioids, in acute intoxication with alcohol, hypnotic, analgesics or psychotropic medicines. Tramadol Hydrochloride must not be used for narcotic withdrawal treatment. Tramadol Hydrochloride should not be given to patients with respiratory depression especially in the presence of cyanosis and excessive bronchial secretions. Tramadol Hydrochloride should not be given to patients with increased intracranial pressure or central nervous system depression due to head injury or cerebral disease.

The following side-effects have been reported. Gastrointestinal system: Nausea, vomiting, dry mouth heartburn, constipation. Central nervous system and psychiatric: Fatigue, sedation, drowsiness, dizziness, confusion, hallucination and seizures.

Tramadol Hydrochloride must not be combined with a MAO-inhibitor or within 14 days of discontinuation of it, as potentiation of serotonergic and noradrenergic effects may result.

Safety during pregnancy and lactation has not been established.

The administration of Tramadol Hydrochloride concurrently with central nervous system depressant medicines is likely to intensify and prolong CNS effects. Patients should be warned not to operate machinery or drive a car while taking Tramadol Hydrochloride.