NEODOL-K Tablet

គុណភាពព្យាបាល
Diclofenac ជាប្រភេទឱសថមានប្រសិទ្ធិភាពសំរាប់ បំបាត់ការឈឺចាប់ បញ្ចុះកំដៅនិងបំបាត់ការរលាក។
- ឱសថនេះប្រើសំរាប់ព្យាបាលនូវរោគសញ្ញារលាកសន្លាក់ រលាកឆ្អឹង រលាកសន្លាក់ឆ្អឹងខ្នងធ្ងន់ធ្ងរ និងរ៉ាំរ៉ៃ
- ប្រើសំរាប់បំបាត់ការឈឺចាប់ពេលមានរដូវ។
កំរិត និង របៀបប្រើ
- ជម្ងឺរលាកសន្លាក់ឆ្អឹង (Osteoarthritis): លេបម្ដង1គ្រាប់ ប្រើ2ទៅ3ដងក្នុង1ថ្ងៃ (100-150ម.ក្រក្នុង1ថ្ងៃ)
- ជម្ងឹរលាកសន្លាក់: លេបម្ដង1គ្រាប់ ប្រើ3ទៅ4ដងក្នុង1ថ្ងៃ (150-200ម.ក្រក្នុង1ថ្ងៃ)
- ជម្ងឹរលាកសន្លាក់ឆ្អឹងខ្នង: លេបម្ដងកន្លះគ្រាប់ ប្រើ4ដងក្នុង1ថ្ងៃ (100-125ម.ក្រក្នុង1ថ្ងៃ)។

Diclofenac is indicated for the acute and chronic treatment of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Diclofenac Potassium is indicated for the management of pain and primary dysmenorrhea.

Dosage and Administration

Osteoarthritis: The recommended dosage is 100-150mg/day in divided doses.

Rheumatoid Arthritis: The dosage is 150-200mg/day in divided doses, 50mg t.i.d. or q.i.d. Diclofenac Potassium.

Ankylosing Spondylitis: The recommended dosage is 100-125mg/day administered as 25mg q.i.d. with an extra 25mg dose at bed time if necessary.

After satisfactory response has been obtained, dosage should be reduced to the minimum dose that provides continuing control of symptoms, usually 75-100mg a day in 3 divided doses.

Analgesia and Primary Dysmenorrhea: Initial dose of 50mg of Diclofenac Potassium, followed by 50mg doses every 8 hours as needed.

ហាមប្រើ៖
- ចំពោះអ្នកងាយមានប្រតិកម្មជាមួយឱសថនេះ
- ចំពោះអ្នកធ្លាប់មានជម្ងឺហឺត កន្ទាលត្រអាក ឬប្រតិកម្មអាល្លែកហ្ស៊ីជាមួយពពួកឱសថ Aspirin ឬពួកឱសថផ្សេងទៀត
- ចំពោះក្មេងតូចអាចបណ្ដាលអោយមាន Choc anaphylactic ម្ដងម្កាល។

Diclofenac Potassium is contraindicated in patients with hypersensitivity to Diclofenac. Diclofenac Potassium should not be given to patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to Diclofenac have been reported in such patients.

ការប្រើឱសថនេះអាចបណ្ដាលអោយឈឺពោះ ឈឺក្បាល ហើមពោះ រាក វិបត្តិរំលាយអាហារ ចង្អោរ ទល់លាមក វិលមុខ។

Peptic ulcer or GI bleeding. Abdominal pain or cramps, headache, fluid retention, abdominal distention, diarrhoea, indigestion, nausea, constipation, flatulence and dizziness may occur.

ប្រតិកម្មរវាងឱសថនេះនិងឱសថផ្សេងៗទៀត៖
- ហាមប្រើឱសថនេះជាមួយពួក Aspirin
- ប្រើឱសថនេះជាមួយពួកDigoxin, Methotrexate, Cyclosporine នាំអោយពុលជាលិកានៃតម្រងនោម (Nephrotoxicity)។

Concomitant administration of Diclofenac potassium and Aspirin is not recommended. Ingestion of Diclofenac may increase serum concentrations of Digoxin and Methotrexate and increase Cyclosporine’s nephrotoxicity. Diclofenac increases Lithium clearance level and increases Lithium plasma level. Concomitant treatment with potassium sparing diuretics may be associated with increased serum potassium levels.

ស្ត្រីមានផ្ទៃពោះត្រូវពិគ្រោះជាមួយគ្រូពេទ្យ។ ស្ត្រីបំបៅកូន ហាមប្រើឱសថនេះ។

There are no adequate and well-controlled studies in pregnant women. Diclofenac Potassium should be used during pregnancy only if the benefits to the mother justify the potential risk to the fetus.

Nursing Mothers: Diclofenac Potassium has been found in the milk of nursing mothers. As with other drugs that are excreted in milk, it is not recommended for use in nursing women.

Pediatric Use: Safety and effectiveness of Diclofenac Potassium in children have not been established.

ប្រុងប្រយ័ត្នចំពោះ ប្រតិកម្មអាល្លែកហ្ស៊ី choc anaphylactic ទល់នោម ហើម ដំបៅក្រពះ ឈាមហូរតាមក្រពះពោះវៀន។

General: Allergic Reactions: allergic reactions including anaphylaxis have been reported with Diclofenac Potassium. Fluid Retention and Edema has been observed in some patients.

Peptic ulceration and gastrointestinal bleeding have been reported in patients receiving Diclofenac. Physicians and Peptic ulceration and gastrointestinal bleeding have been reported in patients receiving Diclofenac Potassium even in the absence of previous G.I. tract symptoms. Elevations of one or more liver tests may occur during Diclofenac therapy.

Diclofenac possesses analgesic, antipyretic and anti-inflammatory activities; it is an inhibitor of cyclooxygenase. In addition, Diclofenac appears to reduce intracellular concentrations of free arachidonate in leukocytes, perhaps by altering the release or uptake of the fatty acid.