DYACHE PLUS0 Tablet

- Acute musculoskeletal painful conditions in adults

- Low back pain

- Acute flares of RA & OA

- Painful and inflammatory ENT conditions (Pharyngitis & tonsillitis)

- Post-operative pain

- Gynaecological pain e.g. Dysmenorrhoea

- Dental pain

- Fractures

Dosage and administration

1 tablet twice a day.

- Patients sensitive to Aceclofenac, Paracetamol or to any of the excipients of the product.

- Patients in whom aspirin or other NSAIDs precipitate attacks of bronchospasm, acute rhinitis or urticaria or patients hypersensitive to these drugs.

- Patients with active or suspected peptic ulcer or gastrointestinal bleeding or bleeding disorders.

- Patients with severe heart failure, hypertension, hepatic or renal insufficiency.

- Last trimester of pregnancy.

Last trimester of pregnancy: Contraindicated

DYACHE PLUS is a combination of Aceclofenac and Paracetamol. Aceclofenac is an NSAID which directly blocks PGE2 secretion at the site o inflammation by inhibiting IL-beta and TNF in the inflammatory cells. Aceclofenac has been demonstrated to inhibit cyclooxygenase (COX) activity and to suppress the PGE2 production by inflammatory cells. Paracetamol is an acetaminophen derivative with analgesic & antipyretic properties.