DIATABS Capsule

Control and symptomatic relief of:

~acute non-specific diarrhea

~chronic diarrhea associated with inflammatory bowel disease.

Reduction of number and volume of discharge in patients with ileostomies and colostomies

In addition to using loperamide for diarrhea.It is important that you replace the fluid and salt loss with the use of oral rehydration solutions(ORS) and/or by drinking plenty of fluids

•For Symptomatic Relief of Acute Diarrhea

Adult Dose: Take 2 capsules initially followed by 1 capsule offer each loose bowel movement.

Or as directed by a doctor.

Maximum dose is 16 mg (8 capsules) per day, Discontinue if there is no improvement after 2 days.

• For Symptomatic Relief of Chronic Diarrhea

Adult Dose: Take 2 capsules initially followed by 1 capsule offer each loose bowel movement

Then reduce loperamide dose to meet individual requirements. When the optimal daily dosage has been established, administer this amount as a single dose or in divided doses.

or, as directed by a doctor.

Average Daily Maintenance Dose: Take 2 to 4 capsules/day, A dosage of five capsules (10 mg) is rarely exceeded.

If no clinical improvement is observed after treatment with 8 capsules/day (16 mg/day) for at least 10 days, symptoms are unlikely to be controlled by further loperamide administration.

~If you are allergic to loperamide or any ingredient in the product.

~If it is for a child under 12 years old.

~If you are pregnant or breastfeeding.

~If you are constipated and also in whom constipation should be avoided.

~If your abdomen is swollen you have abdominal pain.

~If you have acute dysentery which is characterized by blood in stools and high fever.

~If you have pseudomembranous colitis(diarrhea associated with antibiotics),active ulcerative colitis,meningitis,or a history of liver disease.

Loperomide is generally well tolerated:however,dry mouth,abdominal pain, distention or discomfort, nausea, vomiting, fatigue, flatulence, dyspepsia, constipation, epigastric pain, paralytic ileus and toxic megacolon may occur, Loperamide may rarely cause drowsiness and dizziness.

Allergic reactions including unexplained wheezing,shortness of breath, passing out, or swelling of the face and throat have occurred very rarely.

Undesirable effects involving the skin include pruritus, rash, urticaria and extremely rare cases of angioedema and bullous eruption including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis have been rarely reported.

Concomitant administration with the following may result in increased loperamide plasma levels

-Ritonavir (used to treat Human immunodeficiency Virus)

-Quinidine

-Oral desmopressin

-Itraconazole or ketoconazole

-Gemfibrozil

Medicines that slow the action of the stomach and intestines(e.g.,some medicines for depression and cold and allergy medications) as these may increase the constipating effect of loperamide.

Medicines that cause drowsiness since loperamide may also cause drowsiness.

Contraindication