APSYL-S Tablet

ក្រុមហ៊ុនផលិតឱសថ:

 

Kiosyl pharmaceuticals Pvt.Co., LTD,India

ក្រុមហ៊ុនចែកចាយឱសថនៅប្រទេសកម្ពុជា:

 

Sim chayhour pharmaceuticals Co. LTD.

  • សារធាតុសកម្ម
  • ប្រសិទ្ធិភាពព្យាបាល និង កម្រិតប្រើប្រាស់
  • ផលរំខាន
  • អន្តរប្រតិកម្ម
  • ការប្រុងប្រយ័ត្នជាពិសេស
  • សកម្មភាពឱសថ
  • បរិយាយប័ណ្ណឱសថ 
  • សារធាតុសកម្ម

    Aceclofenac 100mg, Paracetamol 500mg, Serratiopeptidase 10mg

  • ប្រសិទ្ធិភាពព្យាបាល និង កម្រិតប្រើប្រាស់

    INDICATIONS:

    It is indicated for: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Pain, inflammation. Acute musculoskeletal disorders and soft tissue inflammation such as periarthritis, sprains, strains, tenosynovitis, bursitis, pain in fractures and dislocation.

    Relief of pain and inflammation associated with orthopedic, dental gynecological and other minor surgical procedures.

    DOSAGE AND DIRECTIONS FOR USE:

    It should be supplied for oral administration in adults. The maximum recommended dose is two tablets daily.

  • ផលរំខាន

    Dyspepsia, abdominal pain and risk in hepatic enzymes, mucocutaneous skin reactions may also occur, dizziness, constipation, vomiting, ulcerative stomatitis, rash, dermatitis, headache, fatigues, allergic reactions, anemia, granulocytopenia, thrombocytopenia, neutropenia, oedema, palpitation, depression, abnormal dreaming, somnolence, insomnia.

  • អន្តរប្រតិកម្ម

    Aceclofenac may increase the plasma concentration of lithium, digoxin and methotrexate. It may increase the activity of anticoagulants, inhibit the activity of diuretics, enhance cyclosporine nephrotoxicity and precipitate convulsions when coadministered with quinolone antibiotics. Coadministration of Aceclofenac with other NSAIDs and corticosteroids are to be avoided due to increased incidence of side-effects. Coadministration of paracetamol with rifampicin, isoniazid, chloramphenicol, antiepileptic drugs and antiviral drugs is to be avoided. Metoclopramide may increase the absorption of Paracetamol whereas excretion Serratiopeptidase can slow blood clotting effect of Anticoagulant/Antiplatelet drugs.

  • ការប្រុងប្រយ័ត្នជាពិសេស

    It may cause dizziness. Driving or operating machinery is to be avoid. Individuals receiving long-term treatment should be regularity monitored for renal function tests, liver function test and blood counts. Caution should be exercised in patients with mild to moderate impairment of cardiac, hepatic or renal function and in elderly patients who are more likely to be suffering from these conditions. Cautions is also required in patients on diuretic therapy or otherwise at risk of hypovolemia.

  • សកម្មភាពឱសថ

    Aceclofenac is an NSAID which directly blocks PGE 2 secretion at the site of inflammation by inhibiting IL-beta and TNF in the inflammatory cells. Aceclofenac has been demonstrated to inhibit cyclooxygenase (COX) activity and to suppress the PGE 2 production by inflammatory cells.

    Paracetamol inhibits the synthesis of prostaglandins in the central nervous system and peripherally blocks pain impulse generation, produces antipyresis from inhibition of hypothalamic heat-regulating center. Serratiopeptidase is a pro-teolytic enzyme, which binds to alpha-2-macroglobulin in the blood, therapy, helps to mask us agnogenicity but retains its enzymatic activity and is slowly transferred to site of inflammation. It hydrolysis bradykinin, histamine and serotonin responsible for oedema.

*ព័ត៌មានឱសថត្រូវបានរៀបរៀងដោយ អ៊ីម៉ាតុគឹ មេឌីក (ខេមបូឌា) ដោយផ្អែកលើប្រភពព័ត៌មានខាងក្រោម។ សម្រាប់ព័ត៌មានលម្អិត សូមស្វែងរកនៅក្នុងក្រដាសព័ត៌មាននៃឱសថនីមួយៗ ឬ សាកសួរទៅកាន់ក្រុមហ៊ុនឱសថឬតំណាងចែកចាយនៃឱសថនីមួយៗ។

ប្រភពព័ត៌មាន៖

- ក្រដាសព័ត៌មាននៃឱសថសម្រាប់អ្នកជំនាញវេជ្ជសាស្ត្រដែលប្រើប្រាស់នៅប្រទេសជប៉ុន (Pharmaceutical and Medical Devices Agency, Pmda): https://www.pmda.go.jp

- ព័ត៌មានសង្ខេបនៃឱសថសម្រាប់អ្នកជំងឺដែលប្រើប្រាស់នៅប្រទេសជប៉ុន: http://www.rad-ar.or.jp