PARACETAMOL WINTHROP Tablet

ក្រុមហ៊ុនផលិតឱសថ:

 

SANOFI-AVENTIS VIETNAM Co.,Ltd., Vietnam

ក្រុមហ៊ុនចែកចាយឱសថនៅប្រទេសកម្ពុជា:

 

SANOFI

  • សារធាតុសកម្ម
  • ប្រសិទ្ធិភាពព្យាបាល និង កម្រិតប្រើប្រាស់
  • ហាមប្រើ
  • ផលរំខាន
  • ស្ត្រីមានផ្ទៃពោះ និង ស្ត្រីបំបៅដោះកូន
  • ការប្រុងប្រយ័ត្នជាពិសេស
  • សកម្មភាពឱសថ
  • បរិយាយប័ណ្ណឱសថ 
  • សារធាតុសកម្ម

  • ប្រសិទ្ធិភាពព្យាបាល និង កម្រិតប្រើប្រាស់

    Symptomatic treatment of mild to moderated pain and/or febrile states.

    Method of administration

    Oral administration

    Swallow the tablets with a large glass of water, milk or fruit juice.

    Dosage

    THIS DOSAGE FORM IS ONLY FOR USE IN ADULTS AND CHILDREN WEIGHING 27KG OR MORE, (i.e. from approximately 8 years of age).

    In adults and children weighing more than 50kg (i.e. approximately 15 years of age and older):

    The usual dosage is 1-2 500mg tablets taken in one dose, repeated as needed at intervals of not less than 4 hours. It is generally not necessary to take more than 3g of paracetamol (i.e. 6 tablets) per day. However, in patients experiencing more intense pain, and on your doctor’s advice, the total dose can be increased to 4g of paracetamol (i.e. 8 tablets) per day.

    However:

    - Dosages greater than 3g of paracetamol per day require medical advice.

    - Never take more than 4g of paracetamol per day (taking into consideration all medicines containing paracetamol).

    Always take doses at least 4 hours apart.

    In Children: The dosage of paracetamol depends on the child’s weight; ages are provided as an indication; and more appropriate pharmaceutical forms used.

    The recommended daily dose of paracetamol is approximately 60mg/kg/day, given in 4 or 6 divided doses, i.e. approximately 15mg/kg every 6 hours or 10mg/kg every 4 hours.

    Children weighing 27-40kg (approximately 8-13 years of age); the dosage is one 500mg tablet per dose, repeated, if necessary, every 6 hours, without exceeding 4 tablets per day.

    Children weighing 41-50kg (approximately 12-15 years of age): the dosage is one 500mg tablet per dose, repeated, if necessary, every 4 hours, without exceeding 6 tablets per day.

    Administration frequency

    Following a regular dose schedule makes it possible to avoid fluctuations in pain or fever.

    Intervals between doses should be:

    * Children should be given doses, including during the night, at regular intervals of at least 4 hours, and preferably 6 hours.

    * Adults should take doses at least 4 hours apart.

    Impaired renal function

    In case of severe renal impairment (creatinine clearance less than 10mL/min), the minimum interval between doses should be preferably 8 hours and at least 4 hours. Paracetamol dose should not exceed 3g (i.e. 6 tablets) per day.

  • ហាមប្រើ

    Allergy to paracetamol or any excipients

    Patients with anemia, or heart, lung, liver, or kidney insufficiency, Glucose-6- phosphate dehydrogenase deficiency.

  • ផលរំខាន

    In certain rare cases, skin rash or redness, or an allergic reaction appearing as sudden swelling of the face and neck, or sudden malaise with a fall in blood pressure may occur. You must stop treatment immediately and inform your physician.

    Very rare instances of thrombocytopenia have been reported.

  • ស្ត្រីមានផ្ទៃពោះ និង ស្ត្រីបំបៅដោះកូន

    The safe use or paracetamol in pregnancy has not been established. Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in recommended dosage. Paracetamol can be used throughout pregnancy under normal conditions of use if necessary.

    Maternal ingestion of paracetamol in usual therapeutic doses does not appear to present a risk to the breastfed infants.

  • ការប្រុងប្រយ័ត្នជាពិសេស

    To avoid risk of overdosage, make sure that concomitant medications are paracetamol-free. Alcohol consumption should be limited or avoided.

  • សកម្មភាពឱសថ

    Paracetamol is rapidly and almost completely absorbed after oral administration. The plasma concentration reaches a maximum within 30-60 minutes. Paracetamol is rapidly distributed to all tissues. Low binding to plasma protein.

*ព័ត៌មានឱសថត្រូវបានរៀបរៀងដោយ អ៊ីម៉ាតុគឹ មេឌីក (ខេមបូឌា) ដោយផ្អែកលើប្រភពព័ត៌មានខាងក្រោម។ សម្រាប់ព័ត៌មានលម្អិត សូមស្វែងរកនៅក្នុងក្រដាសព័ត៌មាននៃឱសថនីមួយៗ ឬ សាកសួរទៅកាន់ក្រុមហ៊ុនឱសថឬតំណាងចែកចាយនៃឱសថនីមួយៗ។

ប្រភពព័ត៌មាន៖

- ក្រដាសព័ត៌មាននៃឱសថសម្រាប់អ្នកជំនាញវេជ្ជសាស្ត្រដែលប្រើប្រាស់នៅប្រទេសជប៉ុន (Pharmaceutical and Medical Devices Agency, Pmda): https://www.pmda.go.jp

- ព័ត៌មានសង្ខេបនៃឱសថសម្រាប់អ្នកជំងឺដែលប្រើប្រាស់នៅប្រទេសជប៉ុន: http://www.rad-ar.or.jp