PHILDOMINA Cream

For the gradual bleaching of hyper pigmented skin conditions such as chloasma, melasma, freckles, lentigines (small macules that resemble freckles) and other unwanted areas of melanin hyperpigmentation.

Since minimal sunlight exposure may reverse the bleaching effect of this preparation, it should be used only at night time or on covered areas of the body.

During the day time, sun blocking or sunscreen preparation or protective clothing should be used to prevent to the bleaching areas from repigmentation.

Dosage and Administration

PHILDOMINA cream should be applied to the affected areas and rubbed well, once daily at the night time. It should not to be used for children under 12 years of age without indication and supervision of the physician.

Patients with history of hypersensitivity or allergic reaction to this product or any of its ingredients.

The safety of treatment with hydroquinone during pregnancy or in children (12 years and under) has not been established.

Hypersensitivity reaction may rarely occur.

Not report so far.

Pregnancy

There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if the potential benefit justified the potential risk to the fetus.

Lactation

The effect of hydroquinone on embryos is not known. It is not known topical hydroquinone is systemic absorbed or excreted in breast milk, so this drug should not be used for breastfeeding women.

Hydroquinone is a skin bleaching agent which may produce unwanted effects if not used as directed. Test for skin sensitivity before using PHILDOMINA cream by applying a small amount to an unbroken patch of skin and checking in 24 hours.

Minorm redness is not a contraindication but where there is itching or vesicle formation of excessive inflammatory response, further treatment is not advised.

Contact with the eyes should be avoided.

If no bleaching or lightening effect is noted after 2 months of treatment, the medication should be discontinued.

Hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation of Tyrosine to 3,4-dihydroxyphenylalanine (dopa) and suppression of the other melanocyte metabolic processes.