AXOL Tablet

Mucolytic agent used in the treatment of respiratory tract disorders associated with viscid mucus.

Dosage and Administration:

For adults: 1 tablet, thrice daily.

For long-term treatment, 1 tablet, twice daily.

To be taken with water after meals.

It is contraindicated in patients who have shown hypersensitivity to this drug.

Gastric discomfort, gastralgia, diarrhoea, nausea, vomiting, constipation and dyspepsia. Other side effects such as skin rash, pruritus and erythema have also been reported.

The benefits of the drug in pregnant women during first trimester should be weighed against a possible risk to the fetus.

The benefits of the drug in pregnant women during first trimester should be weighed against a possible risk to the fetus.

Ambroxol, a metabolite of Bromhexine, is a mucolytic agent capable of increasing sputum volume and reducing its viscosity, improving breathing and reducing cough with no influence on gastric acid secretion.

1. Axol Tablet is a “mucus-modifier”. Its active compound is Ambroxol. Several human studies showed that Ambroxol affects the secret motor activity of serous glands, facilitates the repair of bronchial epithelium, and accelerated mucociliary transport and clearance.

2. Ambroxol, a metabolite of Bromhexine, has been found to stimulate the synthesis of lung surfactant, as the surfactant may play a role in airway mucus transport acting as a lubricant.

3. In several studies, Ambroxol also produced statistically significant symptomatic improvement, measured as difficulty in expectoration, coughing, presence of dyspnea and the auscultatory sign as compared to controls.

4. Absorption after oral administration of Ambroxol was found to be fast and complete. Elimination half-life in the blood was estimated as 20-25 hours in men. In man and rabbit, radioactive-labelled substance was excreted almost completely in to the urine.